LipoVantage® Liposomal Delivery Significantly Enhances Absorption of CoQ10
Sep 17 2025
Key Takeaways
Coenzyme Q10 (CoQ10) plays a vital role in cellular energy production and protection against oxidative stress. However, its absorption from orally administered forms is limited due to its poor water solubility and relatively large molecular weight.
LipoVantage® Liposomal delivery significantly enhances CoQ10 absorption.
- LipoVantage® Liposomal CoQ10 had significantly higher Cmax (+31.3%, p < 0.001) values as compared to non-liposomal CoQ10.
- LipoVantage® Liposomal CoQ10 had significantly higher AUC0-24 (+22.6%, p < 0.001) values as compared to non-liposomal CoQ10.
Impact of liposomal delivery on coenzyme Q10 absorption: a double-blind, placebo-controlled, randomized trial
In a randomized, double-blind, placebo-controlled, crossover study, 18 men and women ingested a single dose of placebo, 100 mg of non-liposomal CoQ10, or 100 mg of LipoVantage® Liposomal CoQ10. Venous blood samples were collected and analyzed for plasma CoQ10 concentrations. Results showed that LipoVantage® Liposomal CoQ10 had significantly higher Cmax (+31.3%, p < 0.001) and AUC0-24 (+22.6%, p < 0.001) values as compared to non-liposomal CoQ10. The conclusion: Liposomal delivery significantly enhances CoQ-10 absorption.
