Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood

Performed at Texas A&M University

In a randomized, double-blind, placebo-controlled study, 59 healthy men and women were either given a placebo of 225 mg Gum Arabic or ashwagandha root and leaf extract coated with a liposomal surface (as Liposomal NooGandha®). This study examined the effects of liposomal ashwagandha supplementation on cognitive function, mood, and markers of health and safety in healthy young men and women. Subjects were administered a fasting blood draw, and then the COMPASS cognitive function test battery (word recall, word recognition, choice reaction time task, picture recognition, digit vigilance task, Corsi Bock test, Stroop test), and profile of mood states (POMS).  The tests were repeated after an hour, and then again after continued supplementation for 30 days.

Study Results

The results showed that when compared to placebo, a single dose of 225 mg of NooGandha® improved all of the measures shown below. After 30 days of supplementation, greater improvements were seen.

• Improved picture recall
• Improved word recall
• Improved reaction time
• Improved executive function
• Decrease in tension
• Decrease in fatigue

Leonard M, Dickerson B, Estes L, Gonzalez DE, Jenkins V, Johnson S, Xing D, Yoo C, Ko J, Purpura M, et al. Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood. Nutrients. 2024; 16(12):1813. https://doi.org/10.3390/nu16121813

https://www.mdpi.com/2072-6643/16/12/1813