Efficacy of fenugreek seed extract on men’s psychological and physical health: a randomized placebo-controlled double-blind clinical trial

Performed at Jacksonville University

A randomized double-blind placebo-controlled trial was employed, using a parallel design, with assessments at baseline, Day 30, and Day 60. Healthy male volunteers were randomized to one of three groups: fenugreek 400 mg/d, fenugreek 500 mg/d, or placebo group. The fenugreek groups reported significant improvements in aging male symptoms, anxiety levels, grip strength, and indicators of HRQoL compared to the placebo group, p’s < 0.05. No adverse events were reported.

Hausenblas HA, Conway KL, Coyle KRM, Barton E, Smith LD, Esposito M, Harvey C, Oakes D, Hooper DR. Efficacy of fenugreek seed extract on men’s psychological and physical health: a randomized placebo-controlled double-blind clinical trial. J Complement Integr Med. 2020 May 22;18(2):445-448. doi: 10.1515/jcim-2019-0101. PMID: 32441668.

https://pubmed.ncbi.nlm.nih.gov/32441668